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KMID : 1007420180160010001
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Mood and Emotion
2018 Volume.16 No. 1 p.1 ~ p.12
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Korean Medication Algorithm for Bipolar Disorder 2018 : Overview
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Kim Won
Bahk Won-Myong
Yoon Bo-Hyun
Jon Duk-In
Seo Jeong-Seok
Lee Jung-Goo
Woo Young-Sup
Jeong Jong-Hyun
Kim Moon-Doo
Sohn In-Ki
Shim Se-Hoon
Song Hoo-Rim
Min Kyung-Jun
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Abstract
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Objectives : The Korean Medication Algorithm for Bipolar Disorder (KMAP-BP), which was first published in 2002 and updated in 2006, 2010 and 2014, is revised again through the expert’s consensus of opinion.
Methods : Out of eighty-four member of the review committee, sixty-one members completed the survey. We analyzed the answers, and thus discussed the data and held a clinician hearing on the results. Therefore, we report the results of KMAP-BP 2018.
Results : The preferred first-step strategies for acute euphoric mania are the combination of mood stabilizer (MS) and atypical antipsychotics (AAP), MS monotherapy and AAP monotherapy. For psychotic mania, combination of MS and AAP, and AAP monotherapy are preferred. The first-step strategies for acute bipolar, mild to moderate, depression are MS monotherapy, lamotrigine (LTG) monotherapy, AAP monotherapy, MS+AAP combination, AAP+LTG combination and MS+LTG combination. For non-psychotic severe depression, the MS+AAP combination, AAP+LTG combination and MS+LTG combination are preferred. For psychotic severe depression, the MS+AAP, AAP+antidepressant (AD) and AAP+LTG are preferred.
Conclusion : We surveyed the expert consensus for the treatment of bipolar disorders and developed KMAP-BP 2018. We hope that this KMAPBP 2018 is going to be helpful for clinicians to treat the patients with bipolar disorder.
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KEYWORD
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Bipolar disorder , KMAP-BP 2018, Pharmacotherapy , Algorithm
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